Grease a 9×13-inch pan. Cut loaf into cubes and place evenly in the pan.

In a bowl, mix eggs, milk, heavy cream, sugar, and vanilla. Pour evenly over bread. Cover pan with plastic wrap and refrigerate overnight.

In a medium-sized bowl, mix flour, brown sugar, cinnamon, and salt. Add butter and mix until crumbly. Place in a ziptop bag and refrigerate overnight.

When ready to bake, sprinkle crumb mixture evenly over the bread mixture.

Bake at 350 degrees Fahrenheit for 45 minutes to one hour, depending on how soft you like it.